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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STXBP1
All Species:
26.97
Human Site:
S506
Identified Species:
42.38
UniProt:
P61764
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P61764
NP_001027392.1
594
67569
S506
Y
P
Y
I
S
T
R
S
S
A
S
F
S
T
T
Chimpanzee
Pan troglodytes
XP_001152683
595
67000
A505
W
P
F
V
S
D
P
A
P
T
A
S
S
Q
A
Rhesus Macaque
Macaca mulatta
XP_001095617
580
66142
S492
Y
P
Y
I
S
T
R
S
S
A
S
F
S
T
T
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q64324
593
66339
A503
W
P
F
V
S
D
P
A
P
V
P
S
S
Q
A
Rat
Rattus norvegicus
P61765
594
67550
S506
Y
P
Y
I
S
T
R
S
S
A
S
F
S
T
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508183
589
67400
S492
Y
P
Y
I
S
T
R
S
S
A
S
F
S
T
T
Chicken
Gallus gallus
Q6R748
594
67454
S506
Y
P
Y
I
S
T
R
S
S
A
S
F
S
T
T
Frog
Xenopus laevis
NP_001093335
595
67691
S507
Y
P
Y
I
S
T
R
S
S
A
S
F
S
T
T
Zebra Danio
Brachydanio rerio
NP_001020353
591
67111
S503
T
K
H
Y
P
Y
I
S
T
R
S
S
S
S
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q07327
597
67832
L510
D
L
R
H
F
P
F
L
E
G
R
A
Q
N
T
Honey Bee
Apis mellifera
XP_396375
585
66573
P498
K
L
D
S
K
H
F
P
F
L
A
G
R
A
A
Nematode Worm
Caenorhab. elegans
P34815
673
76715
A584
T
K
H
F
P
F
L
A
G
R
Q
V
N
Q
G
Sea Urchin
Strong. purpuratus
NP_999834
593
68046
L503
S
D
R
D
Y
P
F
L
S
G
R
N
N
T
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SZ77
662
75299
K547
Y
P
C
M
N
E
P
K
P
T
F
Y
S
G
S
Baker's Yeast
Sacchar. cerevisiae
P30619
724
83462
T559
F
Q
A
G
L
A
N
T
S
A
N
S
S
S
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
63.8
97.6
N.A.
N.A.
62.7
100
N.A.
93.4
97.9
92.4
86.5
N.A.
63.4
63.9
52.1
60.9
Protein Similarity:
100
81.1
97.6
N.A.
N.A.
80.6
100
N.A.
96.1
99.4
97.9
94.6
N.A.
78
79.6
67.4
77.7
P-Site Identity:
100
20
100
N.A.
N.A.
20
100
N.A.
100
100
100
20
N.A.
6.6
0
0
13.3
P-Site Similarity:
100
53.3
100
N.A.
N.A.
46.6
100
N.A.
100
100
100
40
N.A.
6.6
6.6
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.2
22.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.2
42.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
0
7
0
20
0
47
14
7
0
7
20
% A
% Cys:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
7
7
7
0
14
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
7
0
0
7
0
0
0
0
0
0
% E
% Phe:
7
0
14
7
7
7
20
0
7
0
7
40
0
0
7
% F
% Gly:
0
0
0
7
0
0
0
0
7
14
0
7
0
7
14
% G
% His:
0
0
14
7
0
7
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
40
0
0
7
0
0
0
0
0
0
0
0
% I
% Lys:
7
14
0
0
7
0
0
7
0
0
0
0
0
0
0
% K
% Leu:
0
14
0
0
7
0
7
14
0
7
0
0
0
0
0
% L
% Met:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
7
0
7
0
0
0
7
7
14
7
0
% N
% Pro:
0
60
0
0
14
14
20
7
20
0
7
0
0
0
0
% P
% Gln:
0
7
0
0
0
0
0
0
0
0
7
0
7
20
0
% Q
% Arg:
0
0
14
0
0
0
40
0
0
14
14
0
7
0
0
% R
% Ser:
7
0
0
7
54
0
0
47
54
0
47
27
74
14
14
% S
% Thr:
14
0
0
0
0
40
0
7
7
14
0
0
0
47
47
% T
% Val:
0
0
0
14
0
0
0
0
0
7
0
7
0
0
0
% V
% Trp:
14
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
47
0
40
7
7
7
0
0
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _